Synthesis and antioxygenic activities of seabuckthorn flavone-3-ols and analogs.
نویسندگان
چکیده
A practical synthesis of polyhydroxy- and regiospecifically methylated flavone-3-ols which are components of commercial 'seabuckthorn flavone' has been achieved by modified Algar-Flynn-Oyamada method. Antioxidant activities of seabuckthorn extracts, isolated products and a number of flavone-3-ols have been determined. Structure-activity relationships have been discussed. Amongst the compounds tested, gallic acid, which is also present in seabuckthorn, was found to be the most effective antioxidant and radioprotectant.
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ورودعنوان ژورنال:
- Bioorganic & medicinal chemistry letters
دوره 21 18 شماره
صفحات -
تاریخ انتشار 2011